Yvonne Hao

Yvonne Hao joined Flagship Pioneering in 2025 as Chief Operating Officer and General Partner. In this role she leads key functional pillars that support Flagship and its ecosystem of companies, including HR and Talent, Legal and IP, IT/Digital, Communications, Government and Regulatory Affairs, and Facilities/Real Estate. Yvonne also contributes to strategic initiatives and serves on Flagship’s Resource Allocation Committee. In addition, she works alongside Flagship’s Growth Partners to help steward the firm’s later-stage companies, drawing on her experience in company building, operating, and investing.

Yvonne was most recently the Secretary of the Executive Office of Economic Development for the State of Massachusetts. Prior to her role in public service, Yvonne has had more than 25 years of experience as a senior executive, including as Co-founder, Managing Director and Advisor at investment firm Cove Hill Partners and as an Operating Partner at Pillar Ventures. Previously, she was the Chief Operating Officer and Chief Financial Officer of PillPack, where she led the company’s sale to Amazon in 2018. She is also a former Operating Partner at Bain Capital, where she held interim CEO and COO roles, served on boards, and worked closely with portfolio companies. Earlier in her career, she held senior leadership roles at Honeywell and McKinsey & Company.

Yvonne has been a Board Director of companies such as CarGurus, Flywire, Gentherm, ZipRecruiter, and Bose. She also has been involved in the community, and was the Vice Chair of the Board of Trustees of Beth Israel Lahey Health, and is a Trustee Emeriti of her alma mater, Williams College.

Yvonne earned a B.A. in economics and Asian studies from Williams College and an M.Phil. in Development/Economics from the University of Cambridge.